ENVIRONMENTAL BASIC BIOLOGY
博士前期課程理工学研究科 - 理工学専攻
MSGR7170
コース情報
担当教員: 川口 眞理
単位数: 2
年度: 2024
学期: 春学期
曜限: 木5
形式: 対面授業
レベル: 500
アクティブラーニング: なし
他学部履修: 可
評価方法
出席状況
授業参加
レポート
詳細情報
概要
A wide variety of organisms have evolved over 4 billion years. With the recent development of molecular biology, RNA and DNA sequences provide useful information. For example, we can estimate the evolutionary pathway of the species or genes by using the sequences. In this lecture, you will learn how to use such the information based on the bioinforamtic techniques. Students acquire expertise in life sciences necessary to contribute to the development of global environmental sciences, engineering and associated disciplines (Curriculum Policy [MS Program] #2).
目標
The course objective is to gain broad knowledge and expertise about topics of molecular evolution and bioinformatics. Students acquire expertise that will lead to leadership in cutting-edge research and development in Global Environmental Sciences, Engineering and associated disciplines, and ability to develop new technologies and explore new fields. (Diploma Policy [MS Program] #2)
授業外の学習
After each class, students are expected to review the class contents and explore related subjects further.
所要時間: 3.5h
スケジュール
- Introduction
- Building a UNIX environment
- Gene sequence database
- BLAST search
- What is Ortholog?
- Protein domain search
- Preparation of alignment of amino acid sequence
- Principle and practice of neighbor-joining method
- Interpretation of phylogenetic tree
- Principle and practice of maximum likelihood method
- Ancestral sequence estimation: Practice
- Handling of nucleic acid sequence alignment and phylogenetic analysis
- Exploring genes using genome databases
- Estimation of gene structure
教科書
Handouts will be provided when needed.
参考書
書籍情報はありません。